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Liver Cleanse-General Info
 
Summary:
 
Generally Accepted Uses of Artichoke:
  • Loss of appetite
  • Nausea, dyspepsia
  • Irritable bowel syndrome (!), reduces abdominal pain and cramping
  • General support of optimal liver function
  • Stimulates bile flow
  • Lowers cholesterol
  • A remedy for “hang-overs”
 
Traditional and Folklore Uses:
  • Renal insufficiency, edema, arthritis, liver dysfunction, stimulant and tonic, cystitis, prevents gall stones, lowers blood pressure and blood sugar. 
 
Pharmacological Aspects
 
   The medicinal parts of this supplement are derived from dried leaves or fresh flower heads. The compounds used as tracers (and generally believed to be active) are the caffeic acid derivatives such as: chlorogenic acids and cynarin, flavonoids (in particular rutin); and sesquiterpene lactones. A bitter effect on the gastro-intestinal tract has been documented. Artichoke extracts seem to significantly reduce nausea, vomiting, and gas build up; although in the beginning of treatment an initial worsening of flatulence has sometimes been observed. The extract also has a cholagogic, hepatoprotective and lipid reducing effect. In the Natural Database of Medicine an LDL cholesterol lowering effect is mentioned, although it seems to be modest, and requires at least 12 weeks of treatment.  
 
Dosage and Administration
 
   Take one capsule, twice a day, up to six capsules daily, or as advised by your health care practitioner. For irritable bowel syndrome, 500mg, three times daily have been used. Do not take in the presence of gall bladder stones or bile duct blockage. When taking artichoke, caution is recommended if allergic to marigold, chrysanthemums, daisies, ragweed, etc. No significant interactions with drugs, foods, or other supplements are known.
 
What Is Special About The Liver Cleanse Formulation?
 
  • The Liver Cleanse preparation is made from pure, organically grown artichoke flower heads and the edible part of the plant leaves.
  • Normally, manufacturers let the plants dry and, as the need arises, the product is produced. This process adulterates some elements of the original plant. Our artichoke preparation is made from a fresh press juice that is then dried before the capsule making process. Nothing of the original plant is lost and there are no additional additives.
  • The ultimate mix, before the powder goes into the capsules, is made with the Inversina Mixer, an Anthroposophically inspired device that adds an energetic component not found in any other nutritional supplement on the US market. More about this equipment can be found on our web site, www.truebotanica.com.
 
References
Gebhardt, R., Hepatoprotection With Artichoke Extract. Pharm Ztg 1995; 140:34-7.
Gebhardt, R., Inhibition of Cholesterol Biosynthesis in Primary Cultured Rat Hepatocytes By Artichoke (Cynara scolymus L.) Extracts., J Pharmacol Exp Therap 1998; 386:1122-8.
Hammerl, W.H., Kindler K., Kranzl C., et al., Effect of Cynarin (Cynarine) on Hyperlipidemia, Especially on Hypercholesterolemia,. Wien Med Wochenschr 1973; 123:601-5.
Marakis, G., Walker, A.F., Middleton, R.W., et al., Artichoke Leaf Extract Reduces Mild Dyspepsia In An Open Study, Phytomedicine 2002; 9:694-9.
PDR for Herbal Medicines, Third edition, Thompson Publishers
Walker, A.F., Middleton, R.W., Petrowicz, O., Artichoke Leaf Extract Reduces Symptoms of Irritable Bowel Syndrome in a Post-Marketing Surveillance Study, Phytother Res 2001; 15:58-61.
 
This product description sheet is not meant to replace the services of a qualified health care practitioner. This product is not meant to cure any disease and the information supplied here has not been approved by the FDA.


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